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1

Variability in occurrence of multiple prophage genes in Salmonella Typhimurium strains isolated in Slovak Republic

Hana Drahovská, Eva Mikasová, Tomáš Szemes, Andrej Ficek, Milan Sásik, Viktor Majtán, Ján Turna

Journal:

FEMS Microbiology Letters

Année:

2007

Langue:

english

Fichier:

PDF, 252 KB

english, 2007

2

[Handbook of Experimental Pharmacology] || Potential Pharmacological Chaperones for Cystathionine Beta-Synthase-Deficient Homocystinuria

Année:

2017

Langue:

english

Fichier:

PDF, 1016 KB

english, 2017

3

Electron transfer flavoprotein domain II orientation monitored using double electron-electron resonance between an enzymatically reduced, native FAD cofactor, and spin labels

Michael A. Swanson, Velavan Kathirvelu, Tomas Majtan, Frank E. Frerman, Gareth R. Eaton, Sandra S. Eaton

Journal:

Protein Science

Année:

2011

Langue:

english

Fichier:

PDF, 791 KB

english, 2011

4

Effect of cobalt onEscherichia colimetabolism and metalloporphyrin formation

Tomas Majtan, Frank E. Frerman, Jan P. Kraus

Journal:

Année:

2011

Langue:

english

Fichier:

PDF, 461 KB

english, 2011

5

Effect of honey and its major royal jelly protein 1 on cytokine and MMP-9 mRNA transcripts in human keratinocytes

Juraj Majtan, Pawan Kumar, Tomas Majtan, Andrew F. Walls, Jaroslav Klaudiny

Journal:

Experimental Dermatology

Année:

2010

Langue:

english

Fichier:

PDF, 353 KB

english, 2010

6

Transcriptional profiling of bacteriophage BFK20: Coexpression interrogated by “guilt-by-association” algorithm

Tomas Majtan, Nora Halgasova, Gabriela Bukovska, Jozef Timko

Journal:

Année:

2007

Langue:

english

Fichier:

PDF, 736 KB

english, 2007

7

Conformational Properties of Nine Purified Cystathionine β-Synthase Mutants

Hnízda, Aleš, Majtan, Tomas, Liu, Lu, Pey, Angel L., Carpenter, John F., Kodíček, Milan, Kožich, Viktor, Kraus, Jan P.

Journal:

Année:

2012

Langue:

english

Fichier:

PDF, 424 KB

english, 2012

8

Purification and characterization of cystathionine β-synthase bearing a cobalt protoporphyrin

Tomas Majtan, Katherine M. Freeman, Aaron T. Smith, Judith N. Burstyn, Jan P. Kraus

Journal:

Archives of Biochemistry and Biophysics

Année:

2011

Langue:

english

Fichier:

PDF, 435 KB

english, 2011

9

Folding and activity of mutant cystathionine β-synthase depends on the position and nature of the purification tag: Characterization of the R266K CBS mutant

Tomas Majtan, Jan P. Kraus

Journal:

Protein Expression and Purification

Année:

2012

Langue:

english

Fichier:

PDF, 637 KB

english, 2012

10

Purification, crystallization and preliminary crystallographic analysis of human cystathionine β-synthase

Oyenarte, Iker, Majtan, Tomas, Ereño, June, Corral-Rodríguez, María Angeles, Kraus, Jan P., Martínez-Cruz, Luis Alfonso

Journal:

Acta Crystallographica Section F Structural Biology and Crystallization Communications

Année:

2012

Langue:

english

Fichier:

PDF, 597 KB

english, 2012

11

Purification, crystallization and preliminary crystallographic analysis of the full-length cystathionine β-synthase from Apis mellifera

Oyenarte, Iker, Majtan, Tomas, Ereño, June, Corral-Rodríguez, María Angeles, Klaudiny, Jaroslav, Majtan, Juraj, Kraus, Jan P., Martínez-Cruz, Luis Alfonso

Journal:

Acta Crystallographica Section F Structural Biology and Crystallization Communications

Année:

2012

Langue:

english

Fichier:

PDF, 1004 KB

english, 2012

12

Identification of Cystathionine β-Synthase Inhibitors Using a Hydrogen Sulfide Selective Probe

Thorson, Megan K., Majtan, Tomas, Kraus, Jan P., Barrios, Amy M.

Journal:

Angewandte Chemie International Edition

Année:

2013

Langue:

english

Fichier:

PDF, 565 KB

english, 2013

13

Cobalt Cystathionine β-Synthase: A Cobalt-Substituted Heme Protein with a Unique Thiolate Ligation Motif

Smith, Aaron T., Majtan, Tomas, Freeman, Katherine M., Su, Yang, Kraus, Jan P., Burstyn, Judith N.

Journal:

Inorganic Chemistry

Année:

2011

Langue:

english

Fichier:

PDF, 1.66 MB

english, 2011

14

Comparative Study of Enzyme Activity and Heme Reactivity in Drosophila melanogaster and Homo sapiens Cystathionine β-Synthases

Su, Yang, Majtan, Tomas, Freeman, Katherine M., Linck, Rachel, Ponter, Sarah, Kraus, Jan P., Burstyn, Judith N.

Journal:

Année:

2013

Langue:

english

Fichier:

PDF, 2.49 MB

english, 2013

15

Effect of the Disease-Causing R266K Mutation on the Heme and PLP Environments of Human Cystathionine β-Synthase

Smith, Aaron T., Su, Yang, Stevens, Daniel J., Majtan, Tomas, Kraus, Jan P., Burstyn, Judith N.

Journal:

Année:

2012

Langue:

english

Fichier:

PDF, 2.07 MB

english, 2012

16

Identification and characterisation of different proteases in Lucilia sericata medicinal maggots involved in maggot debridement therapy

Valachova, Ivana, Majtan, Tomas, Takac, Peter, Majtan, Juraj

Journal:

Journal of Applied Biomedicine

Année:

2014

Langue:

english

Fichier:

PDF, 1.58 MB

english, 2014

17

The role of surface electrostatics on the stability, function and regulation of human cystathionine β-synthase, a complex multidomain and oligomeric protein

Pey, Angel L., Majtan, Tomas, Kraus, Jan P.

Journal:

Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics

Année:

2014

Langue:

english

Fichier:

PDF, 2.08 MB

english, 2014

18

Correction to Conformational Properties of Nine Purified Cystathionine β-Synthase Mutants

Hnı́zda, Aleš, Majtan, Tomas, Liu, Lu, Pey, Angel L., Carpenter, John F., Kodı́ček, Milan, Kožich, Viktor, Kraus, Jan P.

Journal:

Année:

2012

Langue:

english

Fichier:

PDF, 136 KB

english, 2012

19

DEER Distance Measurement Between a Spin Label and a Native FAD Semiquinone in Electron Transfer Flavoprotein

Swanson, Michael A., Kathirvelu, Velavan, Majtan, Tomas, Frerman, Frank E., Eaton, Gareth R., Eaton, Sandra S.

Journal:

Journal of the American Chemical Society

Année:

2009

Langue:

english

Fichier:

PDF, 551 KB

english, 2009

20

Structural insight into the molecular mechanism of allosteric activation of human cystathionine β-synthase by S -adenosylmethionine

Ereño-Orbea, June, Majtan, Tomas, Oyenarte, Iker, Kraus, Jan P., Martínez-Cruz, Luis Alfonso

Journal:

Proceedings of the National Academy of Sciences

Année:

2014

Langue:

english

Fichier:

PDF, 1.81 MB

english, 2014

21

Marine natural products as inhibitors of cystathionine beta-synthase activity

Thorson, Megan K., Van Wagoner, Ryan M., Harper, Mary Kay, Ireland, Chris M., Majtan, Tomas, Kraus, Jan P., Barrios, Amy M.

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2015

Langue:

english

Fichier:

PDF, 548 KB

english, 2015

22

Changes in hydrogen sulfide production in cystathionine beta-synthase deficiency

Kožich, Viktor, Krijt, Jakub, Sokolová, Jitka, Vozdek, Roman, Melenovská, Petra, Hansíková, Hana, Kratochvílová, Hana, Rodinová, Marie, Majtan, Tomáš, Kraus, Jan P.

Journal:

Année:

2015

Langue:

english

Fichier:

PDF, 91 KB

english, 2015

23

CBS update: Structure, CBS replacement therapy, and H2S production

Majtan, Tomas, Bublil, Erez, Park, InSun, Carrillo, Richard, Ereño-Orbea, June, Martínez-Cruz, Luis Alfonso, Hůlková, Helena, Krijt, Jakub, Kožich, Viktor, Kruger, Warren, Kraus, Jan P.

Journal:

Année:

2015

Langue:

english

Fichier:

PDF, 91 KB

english, 2015

24

Purification, crystallization and preliminary crystallographic analysis of the catalytic core of cystathionine β-synthase from Saccharomyces cerevisiae

Ereño-Orbea, June, Majtan, Tomas, Oyenarte, Iker, Kraus, Jan P., Martínez-Cruz, Luis Alfonso

Journal:

Acta Crystallographica Section F Structural Biology Communications

Année:

2014

Langue:

english

Fichier:

PDF, 1.05 MB

english, 2014

25

Human cystathionine β-synthase (CBS) contains two classes of binding sites for S -adenosylmethionine (SAM): complex regulation of CBS activity and stability by SAM

Pey, Angel L., Majtan, Tomas, Sanchez‑Ruiz, Jose M., Kraus, Jan P.

Journal:

Biochemical Journal

Année:

2013

Langue:

english

Fichier:

PDF, 1.56 MB

english, 2013

26

Thioethers as markers of hydrogen sulfide production in homocystinurias

Kožich, Viktor, Krijt, Jakub, Sokolová, Jitka, Melenovská, Petra, Ješina, Pavel, Vozdek, Roman, Majtán, Tomáš, Kraus, Jan P.

Journal:

Année:

2016

Langue:

english

Fichier:

PDF, 1.57 MB

english, 2016

27

Kinetic stability of cystathionine beta-synthase can be modulated by structural analogs of S-adenosylmethionine: Potential approach to pharmacological chaperone therapy for homocystinuria

Majtan, Tomas, Pey, Angel L., Kraus, Jan P.

Journal:

Année:

2016

Langue:

english

Fichier:

PDF, 1.44 MB

english, 2016

28

Identification of Cystathionine β-Synthase Inhibitors Using a Hydrogen Sulfide Selective Probe

Thorson, Megan K., Majtan, Tomas, Kraus, Jan P., Barrios, Amy M.

Journal:

Angewandte Chemie

Année:

2013

Langue:

english

Fichier:

PDF, 541 KB

english, 2013

29

Oligomeric status of human cystathionine beta-synthase modulates AdoMet binding

Pey, Angel L., Martínez-Cruz, Luis Alfonso, Kraus, Jan P., Majtan, Tomas

Journal:

Année:

2016

Langue:

english

Fichier:

PDF, 816 KB

english, 2016

30

LONG-TERM EFFECT OF ADRENALECTOMY ON CARDIOVASCULAR REMODELING IN PATIENTS WITH PHEOCHROMOCYTOMA

Majtan, Bohumil, Zelinka, Tomáš, Rosa, Ján, Petrák, Ondřej, Krátká, Zuzana, Štrauch, Branislav, Tuka, Vladimír, Vránková, Alice, Michalský, David, Novák, Květoslav, Wichterle, Dan, Widimský, Jiří, Hol

Journal:

Journal of Clinical Endocrinology & Metabolism

Année:

2016

Langue:

english

Fichier:

PDF, 862 KB

english, 2016

31

Engineering and Characterization of an Enzyme Replacement Therapy for Classical Homocystinuria

Majtan, Tomas, Park, Insun, Carrillo, Richard S., Bublil, Erez M., Kraus, Jan P.

Journal:

Biomacromolecules

Année:

2017

Langue:

english

Fichier:

PDF, 4.38 MB

english, 2017

32

Enzyme replacement prevents neonatal death, liver damage, and osteoporosis in murine homocystinuria

Majtan, Tomas, Hůlková, Helena, Park, Insun, Krijt, Jakub, Kožich, Viktor, Bublil, Erez M., Kraus, Jan P.

Journal:

The FASEB Journal

Année:

2017

Langue:

english

Fichier:

PDF, 2.85 MB

english, 2017

33

Biogenesis of Hydrogen Sulfide and Thioethers by Cystathionine Beta-Synthase

Majtan, Tomas, Krijt, Jakub, Sokolova, Jitka, Krizkova, Michaela, Ralat, Maria, Kent, Jana, Gregory III, Jesse F, Kozich, Viktor, Kraus, Jan

Journal:

Antioxidants & Redox Signaling

Année:

2017

Langue:

english

Fichier:

PDF, 1.21 MB

english, 2017

34

Enzyme replacement therapy prevents loss of bone and fat mass in murine homocystinuria

Majtan, Tomas, Park, Insun, Bublil, Erez M., Kraus, Jan P.

Journal:

Année:

2017

Langue:

english

Fichier:

PDF, 785 KB

english, 2017

35

Crystal Structure of cystathionine β-synthase from honeybee Apis mellifera

Giménez-Mascarell, Paula, Majtan, Tomas, Oyenarte, Iker, Ereño-Orbea, June, Majtan, Juraj, Klaudiny, Jaroslav, Kraus, Jan P., Alfonso Martínez-Cruz, Luis

Journal:

Journal of Structural Biology

Année:

2017

Langue:

english

Fichier:

PDF, 2.32 MB

english, 2017

36

Enzyme replacement therapy ameliorates multiple symptoms of murine homocystinuria

Majtan, Tomas, Jones, Wendell, Krijt, Jakub, Park, Insun, Kruger, Warren D., Kožich, Viktor, Bassnett, Steven, Bublil, Erez M., Kraus, Jan P.

Journal:

Molecular Therapy

Année:

2017

Langue:

english

Fichier:

PDF, 2.51 MB

english, 2017

37

Import of TAT-conjugated propionyl-CoA carboxylase using models of propionic acidemia

Collard, Renata, Majtan, Tomas, Park, Insun, Kraus, Jan P.

Journal:

Molecular and Cellular Biology

Année:

2018

Langue:

english

Fichier:

PDF, 5.04 MB

english, 2018

38

Pharmacokinetics and pharmacodynamics of PEGylated truncated human cystathionine beta-synthase for treatment of homocystinuria

Majtan, Tomas, Bublil, Erez M., Park, Insun, Arning, Erland, Bottiglieri, Teodoro, Glavin, Frank, Kraus, Jan P.

Journal:

Année:

2018

Langue:

english

Fichier:

PDF, 1.57 MB

english, 2018

39

Classical homocystinuria: From cystathionine beta-synthase deficiency to novel enzyme therapies

Bublil, Erez M., Majtan, Tomas

Journal:

Année:

2019

Fichier:

PDF, 2.86 MB

2019

40

Cystathionine-Î²-Synthase: Molecular Regulation and Pharmacological Inhibition

Zuhra, Karim, Augsburger, Fiona, Majtan, Tomas, Szabo, Csaba

Journal:

Année:

2020

Fichier:

PDF, 3.60 MB

2020

41

Longâterm uninterrupted enzyme replacement therapy prevents liver disease in murine model of severe homocystinuria

Park, Insun, HÅ¯lkovÃ¡, Helena, Krijt, Jakub, KoÅ¾ich, Viktor, Bublil, Erez M., Majtan, Tomas

Journal:

Année:

2020

Fichier:

PDF, 847 KB

2020

42

Hypermethioninemia Leads to Fatal Bleeding and Increased Mortality in a Transgenic I278T Mouse Model of Homocystinuria

Park, Insun, Johnson, Linda K., Cox, Allaura, Branchford, Brian R., Paola, Jorge Di, Bublil, Erez M., Majtan, Tomas

Journal:

Année:

2020

Fichier:

PDF, 2.91 MB

2020

43

Interplay of Enzyme Therapy and Dietary Management of Murine Homocystinuria

Park, Insun, Bublil, Erez M., Glavin, Frank, Majtan, Tomas

Journal:

Année:

2020

Fichier:

PDF, 2.82 MB

2020